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Search Results for " osteoclast differentiation factor "

Targets

1

Compounds

1

Natural Products

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1925 PLX647 c-Fms , c-Kit
PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).
Cat No. Product Name Synonyms Targets
T16846 Sauristolactam Saurolactam Others
Sauristolactam inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation. Sauristolactam, a natural aristolactam isolated f...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00662 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) Human E. coli
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPJ-00607 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is BAA97257.1.
TMPJ-00674 RANK/TNFRSF11A Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acid...
TMPJ-01466 Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His) Human HEK293 Cells
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ...
TMPY-02575 PPAR gamma/PPARG Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...
TMPH-02264 TNFSF11 Protein, Human, Recombinant (His) Human HEK293 Cells
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator...
TMPJ-00349 RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His) Human HEK293 Cells
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANK...
TMPJ-00799 ANXA2 Protein, Human, Recombinant Human E. coli
Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression r...
TMPJ-01218 M-CSF/CSF1 Protein, Rat, Recombinant Rat HEK293 Cells
Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and different...
TMPJ-01418 CSF1R Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-l...
TMPJ-01419 CSF1R Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-l...
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